CARTHERai™
CAnceR THErapy Rating Algorithm Infrastructure
Technology
Powered by advanced Artificial Intelligence
The CARTHERai™ is a platform ranking cancer therapies based on “Biomarker Signatures” detected in an individual tumor.
It is an infrastructure of algorithms, first extracting all biomarkers from tumor data and then comparing them to “Biomarker Signatures” characterizing responders for each cancer therapy.
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Pipeline
1. Multi-Omics DATA INTEGRATION (genomics, transcriptomics and proteomics) in a AI-driven workflow.
2. DATA PROCESSING to produce multi-level, high-throughput and robust MultiOmics database.
3. BIOMARKER EXTRACTION FROM A COHORT OF RESPONDERS – Extraction and testing of Multi-Omics’ biomarkers associated with specific tumors and patient responses to various anti-cancer therapies.
4. BIOMARKER BUNDLING – Our platform identifies the optimal combinations of biomarker interdependencies and builds AI-powered tools to predict clinical outcomes and understand tumor physiology.
5. TESTING AND VALIDATION of the model in a clinical learning environment.
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Our publications
A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers
The First Report of Biallelic Missense Mutations in the SFRP4 Gene Causing Pyle Disease in Two Siblings
A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection
